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Merck

Therapeutic Antibody Development


 

Robust preclinical methods are crucial for evaluation of potential antibody drugs, ensuring that time, money, and effort are spent on the most promising candidates with greatest therapeutic potential. Recent advances in preclinical modeling and multi-parameter analysis have significantly improved the rigor of experimental evaluation of lead antibody candidates. Our products provide more biologically relevant models and enable more comprehensive assessment to accelerate therapeutic antibody development. 

Preclinical Efficacy and Safety

Cell-based assays, 2D, and 3D models offer invaluable advantages to early drug discovery, providing cost-effective and efficient methods for identifying lead candidates with high affinity, high specificity, and low toxicity. Such models have become crucial for better evaluating the efficacy and toxicology of drugs. By measuring various cellular processes, the most promising candidates can be selected for further development, accelerating drug discovery while shedding comprehensive light on a drug candidate’s potential effects. We provide numerous cellular models, assays, instruments, and reagents to support your drug development needs.

PK/PD and Immunogenicity

These panels enable quantitative investigation of the modulation and expression of dozens of analytes simultaneously, with speed and sensitivity.


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