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Merck

TIMP2

TIMP metallopeptidase inhibitor 2

Sinónimos:
CSC-21K, DDC8
Especie:
ID UniProtKB:
ID del gen:
  • Human(7077) Summary: This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008]
  • Mouse(21858) tissue inhibitor of metalloproteinase 2
  • Rat(29543) TIMP metallopeptidase inhibitor 2
  • Domestic Rabbit(100008689) TIMP metallopeptidase inhibitor 2
  • domestic cat(101083125) TIMP metallopeptidase inhibitor 2
  • Horse(100034134) TIMP metallopeptidase inhibitor 2
  • dog(403633) TIMP metallopeptidase inhibitor 2
  • cow(282093) TIMP metallopeptidase inhibitor 2
  • chicken(374178) TIMP metallopeptidase inhibitor 2
  • domestic guinea pig(100135629) tissue inhibitor of metalloproteinase 2
  • naked mole-rat(101707659) TIMP metallopeptidase inhibitor 2
  • sheep(100217406) TIMP metallopeptidase inhibitor 2

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-TIMP-2 Antibody, clone 2TMP05, clone 2TMP05, Chemicon®, from mouse,
Reactividad de especies
bovine, guinea pig, human, mouse, rabbit, rat
Aplicación
immunohistochemistry
western blot
Anti-TIMP2 antibody, Mouse monoclonal, clone TM8, purified from hybridoma cell culture,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
Anti-TIMP-2 Antibody, clone 67-4H11, clone 67-4H11, Chemicon®, from mouse,
Reactividad de especies
bovine, goat, guinea pig, human, mouse, rabbit, rat
Aplicación
ELISA
immunohistochemistry

western blot
Anti-TIMP2 Antibody, clone 2H23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, guinea pig, human, mouse, porcine, rat, sheep
Aplicación
affinity binding assay
immunohistochemistry

western blot
Anti-TIMP2 Antibody, clone 8R5Q2, Rabbit Monoclonal, ,
Reactividad de especies
african green monkey, human, mouse, rat
Aplicación
western blot

Proteins

Número de producto
Descripción
Especie
TIMP-2 human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human TIMP2,
Especie
human
MISSION® esiRNA, targeting mouse Timp2,
Especie
mouse