SORT1
sortilin 1
Sinónimos:
Gp95, LDLCQ6, NT3
Especie:
Human SORT1 (6272), Mouse Sort1 (20661), Rat Sort1 (83576), cow SORT1 (511591), sheep SORT1 (101104538), domestic guinea pig Sort1 (100718269), dog SORT1 (479915), domestic cat SORT1 (101090199), Horse SORT1 (100061385), chicken SORT1 (100858592)
ID UniProtKB:
ID del gen:
- Human(6272) Summary: This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes; however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p; the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins. [provided by RefSeq, Jul 2008]
- Mouse(20661) sortilin 1
- Rat(83576) sortilin 1
- cow(511591) sortilin 1
- sheep(101104538) sortilin 1
- domestic guinea pig(100718269) sortilin 1
- dog(479915) sortilin 1
- domestic cat(101090199) sortilin 1
- Horse(100061385) sortilin 1
- chicken(100858592) sortilin 1
- naked mole-rat(101698000) sortilin 1
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Sortilin Antibody, clone F11, clone F11, from mouse,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-Sortilin Antibody, clone 4E3.1, clone 4E3.1, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
western blot
western blot
Anti-Sortilin Antibody, serum, Chemicon®,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot