SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
Sinónimos:
CCBR1, xCT
Especie:
Human SLC7A11 (23657), Mouse Slc7a11 (26570), Rat Slc7a11 (310392), naked mole-rat Slc7a11 (101709765), domestic guinea pig Slc7a11 (100735308), domestic cat SLC7A11 (101099374), dog SLC7A11 (483821), chicken SLC7A11 (428731), sheep SLC7A11 (100820755), cow SLC7A11 (524078)
ID UniProtKB:
ID del gen:
- Human(23657) Summary: This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
- Mouse(26570) solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
- Rat(310392) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
- naked mole-rat(101709765) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
- domestic guinea pig(100735308) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
- domestic cat(101099374) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
- dog(483821) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
- chicken(428731) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
- sheep(100820755) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
- cow(524078) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-SLC7A11/xCT antibody produced in rabbit, ,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
western blot
western blot
Anti-xCT Antibody, clone 3A12, ,
Reactividad de especies
human
Aplicación
immunocytochemistry
western blot
western blot
Anti-SLC7A11 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
western blot
esiRNA
Referencia del producto
Descripción
Especie