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Merck

PRMT1

protein arginine methyltransferase 1

Sinónimos:
ANM1, HCP1, HRMT1L2, IR1B4
Especie:
ID UniProtKB:
ID del gen:
  • Human(3276) Summary: This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]
  • Mouse(15469) protein arginine N-methyltransferase 1
  • Rat(60421) protein arginine methyltransferase 1
  • Zebrafish(321974) protein arginine methyltransferase 1
  • naked mole-rat(101721462) protein arginine methyltransferase 1
  • domestic guinea pig(100724273) protein arginine methyltransferase 1
  • Horse(100052097) protein arginine methyltransferase 1
  • cow(520388) protein arginine methyltransferase 1
  • domestic cat(101095389) protein arginine methyltransferase 1
  • dog(476411) protein arginine methyltransferase 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PRMT1 Antibody, Upstate®, from rabbit,
Reactividad de especies
human, mouse
Aplicación
western blot
Anti-PRMT1 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot

Proteins

Referencia del producto
Descripción
Especie
PRMT1 from rat, recombinant, expressed in E. coli, ≥90% (SDS-PAGE), buffered aqueous solution,
Especie
rat

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human PRMT1,
Especie
human
MISSION® esiRNA, targeting mouse Prmt1,
Especie
mouse