PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
Sinónimos:
PLA2G4, cPLA2-alpha
Especie:
Human PLA2G4A (5321), Mouse Pla2g4a (18783), Rat Pla2g4a (24653), dog PLA2G4A (480048), Horse PLA2G4A (100033889), cow PLA2G4A (525072), Zebrafish pla2g4a (559087), domestic guinea pig Pla2g4a (100715719), domestic cat PLA2G4A (101082033), chicken PLA2G4A (396394) ...Más
ID UniProtKB:
ID del gen:
- Human(5321) Summary: This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. [provided by RefSeq, Jul 2008]
- Mouse(18783) phospholipase A2, group IVA (cytosolic, calcium-dependent)
- Rat(24653) phospholipase A2, group IVA (cytosolic, calcium-dependent)
- dog(480048) phospholipase A2, group IVA (cytosolic, calcium-dependent)
- Horse(100033889) phospholipase A2, group IVA (cytosolic, calcium-dependent)
- cow(525072) phospholipase A2, group IVA (cytosolic, calcium-dependent)
- Zebrafish(559087) phospholipase A2, group IVA (cytosolic, calcium-dependent)
- domestic guinea pig(100715719) phospholipase A2, group IVA (cytosolic, calcium-dependent)
- domestic cat(101082033) phospholipase A2, group IVA (cytosolic, calcium-dependent)
- chicken(396394) phospholipase A2, group IVA (cytosolic, calcium-dependent)
- sheep(101111472) phospholipase A2, group IVA (cytosolic, calcium-dependent)
- naked mole-rat(101704061) phospholipase A2, group IVA (cytosolic, calcium-dependent)
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-cPLA2 Antibody, clone 2F4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot