LCK
lymphocyte-specific protein tyrosine kinase
Sinónimos:
LSK, YT16, p56lck, pp58lck
Especie:
Human LCK (3932), Mouse Lck (16818), Rat Lck (313050), chicken LCK (396460), Zebrafish lck (414333), domestic cat LCK (101098805), dog LCK (478151), Domestic Rabbit LCK (100349102), sheep LCK (100216439), cow LCK (508890) ...Más
ID UniProtKB:
ID del gen:
- Human(3932) Summary: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008]
- Mouse(16818) lymphocyte protein tyrosine kinase
- Rat(313050) lymphocyte-specific protein tyrosine kinase
- chicken(396460) lymphocyte-specific protein tyrosine kinase
- Zebrafish(414333) lymphocyte-specific protein tyrosine kinase
- domestic cat(101098805) lymphocyte-specific protein tyrosine kinase
- dog(478151) lymphocyte-specific protein tyrosine kinase
- Domestic Rabbit(100349102) lymphocyte-specific protein tyrosine kinase
- sheep(100216439) lymphocyte-specific protein tyrosine kinase
- cow(508890) lymphocyte-specific protein tyrosine kinase
- Horse(100146139) lymphocyte-specific protein tyrosine kinase
- naked mole-rat(101714396) lymphocyte-specific protein tyrosine kinase
- domestic guinea pig(100728811) lymphocyte-specific protein tyrosine kinase
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Small Molecule - Antagonist
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Lck Antibody, Upstate®, from rabbit,
Reactividad de especies
human
Aplicación
immunoprecipitation (IP)
western blot
western blot
Anti-Phospho-LCK-Y394 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-Lck Antibody, clone 2B20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Anti-Lck Antibody, clone 3A5, clone 3A5, Upstate®, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
immunoprecipitation (IP)
western blot
western blot
Anti-Phospho-Lck-Y505 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Referencia del producto
Descripción
Especie
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC),
Especie
human