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Merck

KCND2

potassium voltage-gated channel, Shal-related subfamily, member 2

Sinónimos:
KV4.2, RK5
Especie:
ID UniProtKB:
ID del gen:
  • Human(3751) Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels. [provided by RefSeq, Jul 2008]
  • Mouse(16508) potassium voltage-gated channel, Shal-related family, member 2
  • Rat(65180) potassium voltage-gated channel, Shal-related subfamily, member 2
  • sheep(101122690) potassium voltage-gated channel, Shal-related subfamily, member 2
  • Domestic Rabbit(100008841) potassium voltage-gated channel, Shal-related subfamily, member 2
  • domestic guinea pig(100720728) potassium voltage-gated channel, Shal-related subfamily, member 2
  • naked mole-rat(101712898) potassium voltage-gated channel, Shal-related subfamily, member 2
  • chicken(374143) potassium voltage-gated channel, Shal-related subfamily, member 2
  • Zebrafish(570188) potassium voltage-gated channel, Shal-related subfamily, member 2
  • dog(491424) potassium voltage-gated channel, Shal-related subfamily, member 2
  • domestic cat(101093262) potassium voltage-gated channel, Shal-related subfamily, member 2
  • cow(540416) potassium voltage-gated channel, Shal-related subfamily, member 2

Custom & Knockdown Gene Products

Small Molecule - Blocker

Número de producto
Descripción
Especie
Guanidina hydrochloride, Molecular Biology, ≥99%,
Especie
human
Guanidina hydrochloride, ≥99% (titration), organic base and chaeotropic agent,
Especie
human
Guanidina hydrochloride, ≥98%,
Especie
human
Guanidine hydrochloride solution, BioUltra, ~8 M in H2O,
Especie
human
Guanidine hydrochloride solution, Colorless liquid, 7.8 - 8.3 M, pH- 4.5 - 5.5,
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human KCND2,
Especie
human
MISSION® esiRNA, targeting mouse Kcnd2,
Especie
mouse