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Merck

IKBKG

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

Sinónimos:
AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IP, IP1, IP2, IPD2, NEMO, ZC2HC9
Especie:
ID UniProtKB:
ID del gen:
  • Human(8517) Summary: This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Aug 2011]
  • Mouse(16151) inhibitor of kappaB kinase gamma
  • Rat(309295) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • Domestic Rabbit(100328905) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • domestic guinea pig(100722308) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • naked mole-rat(101712077) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • dog(612576) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • domestic cat(101086544) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • cow(281855) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • Zebrafish(541530) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • sheep(101107332) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

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Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Parthenolide, ≥98% (HPLC),
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-IKKγ Antibody, Upstate®, from mouse,
Reactividad de especies
human, mouse
Aplicación
western blot
Anti-Phospho-IKKγ-S376 antibody produced in rabbit, ,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human IKBKG,
Especie
human