IFIH1
interferon induced with helicase C domain 1
Sinónimos:
Hlcd, IDDM19, MDA-5, MDA5, RLR-2
Especie:
Human IFIH1 (64135), Mouse Ifih1 (71586), Rat Ifih1 (499801), naked mole-rat Ifih1 (101721395), domestic guinea pig Ifih1 (100717607), cow IFIH1 (535490), sheep IFIH1 (101106234), chicken IFIH1 (424185), dog IFIH1 (488371), domestic cat IFIH1 (101099233)
ID UniProtKB:
ID del gen:
- Human(64135) Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19. [provided by RefSeq, Jul 2012]
- Mouse(71586) interferon induced with helicase C domain 1
- Rat(499801) interferon induced with helicase C domain 1
- naked mole-rat(101721395) interferon induced with helicase C domain 1
- domestic guinea pig(100717607) interferon induced with helicase C domain 1
- cow(535490) interferon induced with helicase C domain 1
- sheep(101106234) interferon induced with helicase C domain 1
- chicken(424185) interferon induced with helicase C domain 1
- dog(488371) interferon induced with helicase C domain 1
- domestic cat(101099233) interferon induced with helicase C domain 1
- Horse(100061257) interferon induced with helicase C domain 1
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-phospho-MDA-5 (Ser104), from rabbit, purified by affinity chromatography,
Reactividad de especies
human
Aplicación
inhibition assay
western blot
western blot
Anti-MDA5 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MDA5 Antibody, clone 2N8Z5, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
western blot