IDO1
indoleamine 2,3-dioxygenase 1
Sinónimos:
IDO, IDO-1, INDO
Especie:
Human IDO1 (3620), Mouse Ido1 (15930), Rat Ido1 (66029), Zebrafish ido1 (571967), dog IDO1 (475574), domestic guinea pig Ido1 (100728309), naked mole-rat Ido1 (101723745), domestic cat IDO1 (101096977), cow IDO1 (506281), sheep IDO1 (100196903)
ID UniProtKB:
ID del gen:
- Human(3620) Summary: This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]
- Mouse(15930) indoleamine 2,3-dioxygenase 1
- Rat(66029) indoleamine 2,3-dioxygenase 1
- Zebrafish(571967) indoleamine 2,3-dioxygenase 1
- dog(475574) indoleamine 2,3-dioxygenase 1
- domestic guinea pig(100728309) indoleamine 2,3-dioxygenase 1
- naked mole-rat(101723745) indoleamine 2,3-dioxygenase 1
- domestic cat(101096977) indoleamine 2,3-dioxygenase 1
- cow(506281) indoleamine 2,3-dioxygenase 1
- sheep(100196903) indoleamine 2,3-dioxygenase 1
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-IDO-1 Antibody, clone 4B7 | MABF850, clone 4B7, from mouse,
Reactividad de especies
mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-Indoleamine 2,3-dioxygenase Antibody, clone 10.1, clone 10.1, Chemicon®, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-Ido1, clone 8G11 Antibody, clone 8G11, from mouse,
Reactividad de especies
mouse
Aplicación
flow cytometry
western blot
western blot
Anti-IDO Antibody, clone 1F8.2, clone 1F8.2, from mouse,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-IDO1 Antibody, clone 1B17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Referencia del producto
Descripción
Especie