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Merck

HTRA2

HtrA serine peptidase 2

Sinónimos:
OMI, PARK13, PRSS25
Especie:
ID UniProtKB:
ID del gen:
  • Human(27429) Summary: This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(64704) HtrA serine peptidase 2
  • Rat(297376) HtrA serine peptidase 2
  • domestic guinea pig(100734064) HtrA serine peptidase 2
  • dog(475782) HtrA serine peptidase 2
  • cow(523039) HtrA serine peptidase 2
  • fruit fly(41756) CG8464 gene product from transcript CG8464-RB
  • sheep(101120228) HtrA serine peptidase 2
  • chicken(395990) HtrA serine peptidase 2
  • naked mole-rat(101725239) HtrA serine peptidase 2
  • Domestic Rabbit(100338967) HtrA serine peptidase 2
  • domestic cat(768259) HtrA serine peptidase 2

Custom & Knockdown Gene Products

  • siRNA

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-HTRA2 Antibody, clone 4H8C4, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human HTRA2,
Especie
human