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Merck

HTR4

5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

Sinónimos:
5-HT4, 5-HT4R
Especie:
ID UniProtKB:
ID del gen:
  • Human(3360) Summary: This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]
  • Mouse(15562) 5 hydroxytryptamine (serotonin) receptor 4
  • Rat(25324) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • Horse(100034053) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • domestic cat(101088723) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • sheep(101117928) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • cow(317708) 5-hydroxytryptamine (serotonin) receptor 4
  • domestic guinea pig(100135548) 5 hydroxytryptamine (serotonin) receptor 4
  • chicken(416150) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • dog(489198) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • naked mole-rat(101707865) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
Tegaserod maleate, ≥98% (HPLC),
Especie
human
Metoclopramide, VETRANAL®, analytical standard,
Especie
human
Metoclopramide, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Metoclopramide hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Especie
human
Quipazine maleate salt, ,
Especie
human

Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
DCEBIO, ≥98% (HPLC), solid,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
SB-204070 hydrochloride, solid, ≥97% (HPLC),
Especie
human
ML 10302, ≥98%, solid,
Especie
rat
Metoclopramide, VETRANAL®, analytical standard,
Especie
human
GR 113808, ≥98% (HPLC), solid,
Especie
rat, human
Metoclopramide, European Pharmacopoeia (EP) Reference Standard,
Especie
human

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Mifepristone, ≥98%,
Especie
human, mouse, rat

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Especie
human

Small Molecule - Metabolite

Referencia del producto
Descripción
Especie
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Especie
human

Small Molecule - Precursor

Referencia del producto
Descripción
Especie
5-Hydroxy-L-tryptophan, powder,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human HTR4,
Especie
human