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Merck

GLUD1

glutamate dehydrogenase 1

Sinónimos:
GDH, GDH1, GLUD
Especie:
ID UniProtKB:
ID del gen:
  • Human(2746) Summary: This gene encodes glutamate dehydrogenase protein; a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion and activating mutations in this gene are a common cause of congenital hyperinsulinism. This enzyme is allosterically activated by ADP and inhibited by GTP and ATP. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Multiple pseudogenes of this gene are present in humans.[provided by RefSeq, Sep 2009]
  • Mouse(14661) glutamate dehydrogenase 1
  • Rat(24399) glutamate dehydrogenase 1
  • naked mole-rat(101699446) glutamate dehydrogenase 1
  • domestic guinea pig(100722523) glutamate dehydrogenase 1
  • sheep(443239) glutamate dehydrogenase 1
  • cow(281785) glutamate dehydrogenase 1
  • dog(100684847) glutamate dehydrogenase 1
  • chicken(423612) glutamate dehydrogenase 1

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-GLUD1 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-Glud1 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
baboon, bat, bovine, human, monkey, mouse
Aplicación
immunohistochemistry
western blot

Proteins

Número de producto
Descripción
Especie
Glutamate Dehydrogenase (GlDH), from beef liver,
Especie
cow
L-Glutamic Dehydrogenase from bovine liver, Type III, lyophilized powder, ≥20 units/mg protein,
Especie
cow
L-Glutamic Dehydrogenase from bovine liver, Type I, ammonium sulfate suspension, ≥40 units/mg protein,
Especie
cow

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human GLUD1,
Especie
human
MISSION® esiRNA, targeting mouse Glud1,
Especie
mouse