DNASE1
deoxyribonuclease I
Sinónimos:
DNL1, DRNI
Especie:
Human DNASE1 (1773), Mouse Dnase1 (13419), Rat Dnase1 (25633), naked mole-rat Dnase1 (101713435), domestic guinea pig Dnase1 (100718441), sheep DNASE1 (101122154), Horse DNASE1 (100034219), cow DNASE1 (282217), Domestic Rabbit DNASE1 (100009513), dog DNASE1 (403413) ...Más
ID UniProtKB:
ID del gen:
- Human(1773) Summary: This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
- Mouse(13419) deoxyribonuclease I
- Rat(25633) deoxyribonuclease I
- naked mole-rat(101713435) deoxyribonuclease I
- domestic guinea pig(100718441) deoxyribonuclease I
- sheep(101122154) deoxyribonuclease I
- Horse(100034219) deoxyribonuclease I
- cow(282217) deoxyribonuclease I
- Domestic Rabbit(100009513) deoxyribonuclease I
- dog(403413) deoxyribonuclease I
- domestic cat(101096195) deoxyribonuclease I
- chicken(395725) deoxyribonuclease I
- Zebrafish(436947) deoxyribonuclease I
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-DNASE1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, human, rat
Aplicación
western blot
Anti-DNASE1 (N-terminal) antibody produced in rabbit FITC conjugated, affinity isolated antibody,
Reactividad de especies
bovine, human, rat
Aplicación
Anti-DNASE1 (N-terminal) antibody produced in rabbit HRP conjugated, affinity isolated antibody,
Reactividad de especies
bovine, human, rat
Aplicación
Proteins
Referencia del producto
Descripción
Especie
Desoxirribonucleasa I from bovine pancreas, lyophilized powder, Protein ≥85 %, ≥400 Kunitz units/mg protein,
Especie
Desoxirribonucleasa I from bovine pancreas, Type IV, lyophilized powder, ≥2,000 Kunitz units/mg protein,
Especie
Desoxirribonucleasa I from bovine pancreas, Type II-S, lyophilized powder, Protein ≥80 %, ≥2,000 units/mg protein,
Especie
Desoxirribonucleasa I from bovine pancreas, Type II, lyophilized powder, Protein ≥80 %, ≥2,000 units/mg protein,
Especie
DNase I recombinant, grade I, from bovine pancreas, expressed in Pichia pastoris,
Especie
cow