Saltar al contenido
Merck

COL18A1

collagen, type XVIII, alpha 1

Sinónimos:
KNO, KNO1, KS
Especie:
ID UniProtKB:
ID del gen:
  • Human(80781) Summary: This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
  • Mouse(12822) collagen, type XVIII, alpha 1
  • Rat(85251) collagen, type XVIII, alpha 1
  • chicken(373978) collagen, type XVIII, alpha 1
  • domestic cat(101086496) collagen, type XVIII, alpha 1
  • dog(100687767) collagen, type XVIII, alpha 1
  • dog(100126771) collagen, type XVIII, alpha 1
  • sheep(101106232) collagen, type XVIII, alpha 1
  • naked mole-rat(101705854) collagen, type XVIII, alpha 1
  • domestic guinea pig(100733184) collagen, type XVIII, alpha 1
  • Zebrafish(564123) collagen type XVIII, alpha 1
  • cow(508076) collagen, type XVIII, alpha 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-COL18A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-Endostatin Antibody, clone 1837.46, clone 1837.46, Upstate®, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
western blot
Anti-Endostatin Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot

Proteins

Referencia del producto
Descripción
Especie
Endostatin human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human COL18A1,
Especie
human
MISSION® esiRNA, targeting mouse Col18a1,
Especie
mouse