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Merck

CDK9

cyclin-dependent kinase 9

Sinónimos:
C-2k, CDC2L4, CTK1, PITALRE, TAK
Especie:
ID UniProtKB:
ID del gen:
  • Human(1025) Summary: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008]
  • Mouse(107951) cyclin-dependent kinase 9 (CDC2-related kinase)
  • Rat(362110) cyclin-dependent kinase 9
  • domestic guinea pig(100725846) cyclin-dependent kinase 9
  • naked mole-rat(101722666) cyclin-dependent kinase 9
  • sheep(101109788) cyclin-dependent kinase 9
  • Zebrafish(321602) cyclin-dependent kinase 9 (CDC2-related kinase)
  • cow(520580) cyclin-dependent kinase 9
  • dog(491325) cyclin-dependent kinase 9
  • chicken(417226) cyclin-dependent kinase 9
  • fruit fly(37586) Cyclin-dependent kinase 9
  • domestic cat(101097767) cyclin-dependent kinase 9

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CDK9 Antibody, clone 1F9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey, mouse, rat
Aplicación
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-CDK9 antibody produced in rabbit, ,
Reactividad de especies
Aplicación
immunohistochemistry
western blot
Anti-Phospho-CDK9-T186 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Flavopiridol hydrochloride, ≥98% (HPLC), powder,
Especie
human
Roscovitine, ≥98% (TLC),
Especie
human, mouse, rat
Olomoucine, ≥98% (HPLC),
Especie
human, rat

Proteins

Referencia del producto
Descripción
Especie
Cdk9/Cyclin T1 Protein, active, 10 µg, Active, C-terminal 6His-tagged, full length recombinant, human Cdk9 co-expressed with untagged, full-length human Cyclin T1, for use in Kinase Assays.,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human CDK9,
Especie
human