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Merck

CAMK2A

calcium/calmodulin-dependent protein kinase II alpha

Sinónimos:
CAMKA
Especie:
ID UniProtKB:
ID del gen:
  • Human(815) Summary: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]
  • Mouse(12322) calcium/calmodulin-dependent protein kinase II alpha
  • Rat(25400) calcium/calmodulin-dependent protein kinase II alpha
  • Zebrafish(550436) calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha
  • Domestic Rabbit(100341507) calcium/calmodulin-dependent protein kinase II alpha
  • dog(612941) calcium/calmodulin-dependent protein kinase II alpha
  • domestic cat(101084342) calcium/calmodulin-dependent protein kinase II alpha
  • cow(530719) calcium/calmodulin-dependent protein kinase II alpha
  • naked mole-rat(101722229) calcium/calmodulin-dependent protein kinase II alpha
  • domestic guinea pig(100727059) calcium/calmodulin-dependent protein kinase II alpha
  • Horse(100071654) calcium/calmodulin-dependent protein kinase II alpha
  • chicken(374175) calcium/calmodulin-dependent protein kinase II alpha

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Número de producto
Descripción
Especie
N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride, ,
Especie
human

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-CaM Kinase II Antibody, α subunit, clone 6G9, clone 6G9, Upstate®, from mouse,
Reactividad de especies
bovine, rat
Aplicación
immunohistochemistry
western blot
Anticuerpo anti-fosfo-CaM cinasa II, subunidad α, (Thr286), clon 22B1, clone 22B1, Upstate®, from mouse,
Reactividad de especies
rat
Aplicación
western blot
Anti-CaM Kinase II Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
bovine, chicken, guinea pig, hamster, human, mouse, rabbit, rat
Aplicación
western blot
Monoclonal Anti-CAMK2A antibody produced in mouse, clone 2C12, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence

western blot
Anti CaMKII Antibody, clone 23GB5920, Rabbit Monoclonal, clone 23GB5920, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
western blot

Small Molecule - Inhibitor

Número de producto
Descripción
Especie
Adenina, ≥99%,
Especie
human, rat, mouse
Adenina, BioReagent, suitable for cell culture,
Especie
human, rat, mouse
Adenina, BioReagent, suitable for plant cell culture, ≥99%,
Especie
human, rat, mouse

Proteins

Número de producto
Descripción
Especie
CAMK2α, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
Calmodulin-dependent Protein Kinase II fragment 290-309, ≥97% (HPLC),
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human CAMK2A,
Especie
human
MISSION® esiRNA, targeting mouse Camk2a,
Especie
mouse

Small Molecule - Substrate

Número de producto
Descripción
Especie
Autocamtide 2-related inhibitory peptide, ≥97% (HPLC), lyophilized powder,
Especie
mouse, rat, human