BAD
BCL2-associated agonist of cell death
Sinónimos:
BBC2, BCL2L8
Especie:
Human BAD (572), Mouse Bad (12015), Rat Bad (64639), dog BAD (483763), domestic cat BAD (768269), sheep BAD (780444), cow BAD (615013), naked mole-rat Bad (101726042), domestic guinea pig Bad (100734151)
ID UniProtKB:
ID del gen:
- Human(572) Summary: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]
- Mouse(12015) BCL2-associated agonist of cell death
- Rat(64639) BCL2-associated agonist of cell death
- dog(483763) BCL2-associated agonist of cell death
- domestic cat(768269) BCL2-associated agonist of cell death
- sheep(780444) BCL2-associated agonist of cell death
- cow(615013) BCL2-associated agonist of cell death
- naked mole-rat(101726042) BCL2-associated agonist of cell death
- domestic guinea pig(100734151) BCL2-associated agonist of cell death
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Small Molecule - Antagonist
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-phospho BAD Antibody (Ser155), from rabbit, purified by affinity chromatography,
Reactividad de especies
bovine, canine, human, mouse, rat
Aplicación
immunoprecipitation (IP)
inhibition assay
western blot
inhibition assay
western blot
Anti-Phospho-Bad-S112 antibody produced in rabbit, ,
Reactividad de especies
human
Aplicación
western blot
Anti-Phospho-Bad (Ser99) Antibody, from rabbit,
Reactividad de especies
human
Aplicación
western blot
Anti-Phospho- Bad (Ser75) Antibody, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-Bad antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
esiRNA
Referencia del producto
Descripción
Especie