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Merck

ADRB2

adrenoceptor beta 2, surface

Sinónimos:
ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Especie:
ID UniProtKB:
ID del gen:
  • Human(154) Summary: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11555) adrenergic receptor, beta 2
  • Rat(24176) adrenoceptor beta 2, surface
  • cow(281605) adrenergic, beta-2-, receptor, surface
  • Horse(100060659) adrenoceptor beta 2, surface
  • domestic cat(493767) adrenoceptor beta 2, surface
  • naked mole-rat(101708921) adrenoceptor beta 2, surface
  • domestic guinea pig(100722663) adrenoceptor beta 2, surface
  • dog(403910) adrenoceptor beta 2, surface
  • chicken(427623) adrenergic, beta-2-, receptor, surface
  • Domestic Rabbit(100340821) adrenoceptor beta 2, surface
  • sheep(100170320) adrenoceptor beta 2, surface

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
(−)-Isoproterenol hydrochloride, ,
Especie
human
Salbutamol, ,
Especie
human
Formoterol fumarate dihydrate, >98% (HPLC),
Especie
human
Fenoterol hydrobromide, ,
Especie
human
Albuterol sulfate, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
ICI 118,551 hydrochloride, ≥98% (HPLC), powder,
Especie
human
Propranolol hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Propranolol hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Timolol maleate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Propranolol for system suitability, European Pharmacopoeia (EP) Reference Standard,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-β2-Adrenergic Receptor Antibody, clone 2B23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-Adrenoceptor β-2 Antibody, Chemicon®, from rabbit,
Reactividad de especies
human
Aplicación
immunohistochemistry

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
Sotalol hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human
(±)-Sotalol hydrochloride, ≥98% (TLC), powder,
Especie
human
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
Especie
human
Propafenone hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Propafenone hydrochloride, ,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Adrb2,
Especie
mouse
MISSION® esiRNA, targeting human ADRB2,
Especie
human