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About This Item
Empirical Formula (Hill Notation):
C29H36N6O10
Molecular Weight:
628.63
UNSPSC Code:
12352200
NACRES:
NA.32
Assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥75%
storage condition
protect from light
storage temp.
−20°C
Amino Acid Sequence
Ac-Tyr-Val-Ala-Asp-pNA
Application
Ac-YVAD-pNa (acetyl-Tyr-Val-Ala-Asp-p-nitroanalide) is a selective chromogenic substrate for the detection of Interleukin-1b Converting Enzyme/caspase 1.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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C Bossenmeyer-Pourié et al.
Neuroscience, 95(4), 1157-1165 (2000-02-22)
To further explore the contribution of caspase-1/interleukin-1beta-convening enzyme in the consequences of hypoxia in developing brain neurons, its temporal expression profile was analysed by immunohistochemistry and western blotting in cultured neurons from the embryonic rat forebrain subjected to a hypoxic
Ori Nov et al.
Endocrinology, 151(9), 4247-4256 (2010-07-28)
Central obesity is frequently associated with adipose tissue inflammation and hepatic insulin resistance. To identify potential individual mediators in this process, we used in vitro systems and assessed if insulin resistance in liver cells could be induced by secreted products
Natasha Ann Pereira et al.
Biochemical and biophysical research communications, 377(3), 873-877 (2008-11-04)
Many designated substrates and inhibitors have been widely used to investigate the roles of caspases in apoptotic death during mammalian cell culture. However, the specificities of these substrates and inhibitors have not been systematically evaluated. As a result, conclusions on
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