RAB0325
Inhibin-B EIA Kit
for serum, plasma, culture supernatant and cell lysates
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About This Item
UNSPSC Code:
41123300
NACRES:
NA.32
Recommended Products
species reactivity
rat, mouse, human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
enzyme immunoassay: suitable
input
sample type plasma
sample type cell lysate
sample type serum
sample type culture supernatant(s)
assay range
inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 2 pg/mL
standard curve range: 1-10000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... INHBB(3625)
General description
Inhibin-B (INHBB) is a heterodimeric glycoprotein with disulfide-linkage. It is produced by granulosa cells in the ovary. The INHBB gene is mapped to human chromosome 2q14.2. Inhibin-B inhibits follicle-stimulating hormone (FSH) secretion and synthesis. It may serve in diagnosing testicular function and as an indicator of Sertoli cell numbers and function. Inhibin B may serve as a marker for spermatogenesis.
The Inhibin B Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting Inhibin B peptide based on the principle of Competitive Enzyme Immunoassay. EIA-INB-1 targets the β B subunit, and therefore theoretically detects Activin B and Activin AB in addition to Inhibin B.
The Inhibin B Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting Inhibin B peptide based on the principle of Competitive Enzyme Immunoassay. EIA-INB-1 targets the β B subunit, and therefore theoretically detects Activin B and Activin AB in addition to Inhibin B.
Immunogen
Inhibin-B, synthetic peptide
Application
Inhibin-B EIA Kit has been used in quantification of Inhibin-B using enzyme-linked immunosorbent assay (ELISA) in Zika virus-infected human Sertoli cells (HSerC) and 8-week-old mice.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
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S J Meachem et al.
European journal of endocrinology, 145(5), 561-571 (2001-11-27)
The recent availability of specific inhibin assays has demonstrated that inhibin B is the relevant circulating inhibin form in the human male. Inhibin B is a dimer of an alpha and a betaB subunit. It is produced exclusively by the
M Chada et al.
Physiological research, 52(3), 341-346 (2003-06-07)
Inhibin B, produced by granulosa cells in the ovary, is a heterodimeric glycoprotein suppressing synthesis and secretion of the follicle stimulating hormone (FSH). The aim of the present study was to determine hormone profiles of inhibin B, FSH, luteinizing hormone
Mahamud-Ur Rashid et al.
PLoS neglected tropical diseases, 14(6), e0008335-e0008335 (2020-06-09)
Zika virus (ZIKV), a neglected tropical disease until its re-emergence in 2007, causes microcephaly in infants and Guillain-Barré syndrome in adults. Its re-emergence and spread to more than 80 countries led the World Health Organization in 2016 to declare a
R Mayor et al.
British journal of cancer, 100(10), 1534-1539 (2009-04-23)
Large chromosomal regions can be suppressed in cancer cells as denoted by hypermethylation of neighbouring CpG islands and downregulation of most genes within the region. We have analysed the extent and prevalence of long-range epigenetic silencing at 2q14.2 (the first
Liang-Yu Chen et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(7), 1829-1834 (2016-02-03)
Spermatogonial stem cells (SSCs) are a subpopulation of undifferentiated spermatogonia located in a niche at the base of the seminiferous epithelium delimited by Sertoli cells and peritubular myoid (PM) cells. SSCs self-renew or differentiate into spermatogonia that proliferate to give
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