P0747

8-MA-cAMP

≥98% (HPLC), solid

• Synonym(s): 8-Methylaminoadenosine-3′,5′-cyclic monophosphate sodium salt
• Empirical Formula (Hill Notation): C₁₁H₁₄N₆O₆PNa
• CAS Number: 33823-18-6
• Molecular Weight: 380.23
• MDL number: MFCD04113731
• UNSPSC Code: 12352200
• PubChem Substance ID: 24724571

Properties

• Assay: ≥98% (HPLC)
• form: solid
• packaging: pkg of 10 μmol
• color: white
• solubility: H₂O: freely soluble
• shipped in: dry ice
• storage temp.: −70°C
• SMILES string: [Na+].CNc1nc2c(N)ncnc2n1[C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O
• InChI: 1S/C11H15N6O6P.Na/c1-13-11-16-5-8(12)14-3-15-9(5)17(11)10-6(18)7-4(22-10)2-21-24(19,20)23-7;/h3-4,6-7,10,18H,2H2,1H3,(H,13,16)(H,19,20)(H2,12,14,15);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1
• InChI key: PYXGPPLPPUIPRE-MCDZGGTQSA-M

Description

Biochem/physiol Actions

Selective cAMP-dependent protein kinase (PKA) activator. Site selective cyclic AMP analogue with similar affinity to site B of both protein kinase A type I and II. Priming analogue which acts synergistically together with analogues showing site A preference. Together with e.g. 8-piperidino cAMP, selective stimulation of type I can be achieved.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves