Skip to Content
Merck
All Photos(1)

Key Documents

P0314

Sigma-Aldrich

Prostaglandin F methyl ester

~5 mg/mL in methyl acetate, ≥95% (HPLC)

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C21H36O5
CAS Number:
Molecular Weight:
368.51
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

Assay

≥95% (HPLC)

concentration

~5 mg/mL in methyl acetate

storage temp.

−20°C

SMILES string

CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(=O)OCC

InChI

1S/C22H38O5/c1-3-5-8-11-17(23)14-15-19-18(20(24)16-21(19)25)12-9-6-7-10-13-22(26)27-4-2/h6,9,14-15,17-21,23-25H,3-5,7-8,10-13,16H2,1-2H3/b9-6-,15-14+/t17-,18+,19+,20-,21+/m0/s1

InChI key

KRDFNHLEMLCWKD-GWSKAPOCSA-N

Biochem/physiol Actions

Constricts an isolated human smooth muscle; methyl ester form of prostaglandin F2α which is a luteolytic prostaglandin (induces parturition; pulmonary vasoconstrictor).

Packaging

Packaged under Argon.

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

15.0 °F

Flash Point(C)

-9.45 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

The ocular hypotensive effects and side effects of prostaglandins on the eyes of experimental animals.
L Z Bito et al.
Progress in clinical and biological research, 312, 349-368 (1989-01-01)
Zhonghua fu chan ke za zhi, 25(1), 31-34 (1990-01-01)
Abortion was attempted in 316 healthy women in early pregnancy within 7 weeks with the RU486 alone (600mg in a single oral dose) or in combination with a PG (15-dl-methyl-PGF2 alpha-methyl-ester) 1 mg suppository. The result of using RU 486
B V Praveen et al.
International journal of clinical pharmacology, therapy, and toxicology, 30(1), 7-12 (1992-01-01)
A prospective randomized, controlled study was done to compare the efficacy and safety of 15(s) 15 Me PGF2 alpha intravesical instillation and 1% alum vesical irrigation in the control of vesical hematuria which persisted even after continuous bladder irrigation with
A Alm et al.
Progress in clinical and biological research, 312, 447-458 (1989-01-01)
A lipid-soluble PG ester such as PGF2 alpha-IE reduces IOP in the human eye when given in considerably lower doses than are needed for the tromethamine salt of this PG to do so. However, with the pharmaceutical composition now used
L Mastalerz
Polskie Archiwum Medycyny Wewnetrznej, 93(2), 179-183 (1995-02-01)
Prostaglandins (PGs) belong to the family of eicosanoids. A main substrate in their biosynthesis is arachidonic acid. Involvement of PGs in regulation of bronchial activity is a complex process and far from being fully understood. In 1968 it was shown

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service