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I8510

Sigma-Aldrich

Anti-Insulin antibody produced in guinea pig

whole antiserum

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About This Item

MDL number:
UNSPSC Code:
12352203

biological source

guinea pig

conjugate

unconjugated

antibody form

whole antiserum

clone

polyclonal

contains

15 mM sodium azide

species reactivity

bovine, human, pig

technique(s)

radioimmunoassay: 1:80,000

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... INS(3630)

Immunogen

pig insulin

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)
Immunohistochemistry (1 paper)

Reconstitution

Dilute with buffer: 0.05 M phosphate, pH 7.4, 0.15 M sodium chloride, 0.5% human serum albumin and 15 mM sodium azide.

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R A Silvestre et al.
British journal of pharmacology, 128(3), 795-801 (1999-10-12)
1. Diadenosine triphosphate (AP3A) and diadenosine tetraphosphate (AP4A) are released by various cells (e.g. platelets and chromaffin cells), and may act as extracellular messengers. In pancreatic B-cells, AP3A and AP4A are inhibitors of the ATP-regulated K+ channels, and glucose increases
J K Mills et al.
Journal of dairy science, 93(9), 4262-4273 (2010-08-21)
The objective of this study was to determine the effects of feeding calves isocaloric, isonitrogenous diets that varied in the amount and type of fatty acids on growth, response to an insulin challenge, and body composition. Thirty-six calves were assigned
Jeremy A Lavine et al.
Molecular endocrinology (Baltimore, Md.), 22(12), 2716-2728 (2008-10-11)
Type 1 and type 2 diabetes result from a deficit in insulin production and beta-cell mass. Methods to expand beta-cell mass are under intensive investigation for the treatment of type 1 and type 2 diabetes. We tested the hypothesis that
R A Silvestre et al.
The Journal of endocrinology, 196(2), 283-290 (2008-02-07)
Kisspeptins are a family of peptides encoded by the KISS1 gene, which binds to G-protein-coupled receptor (GPR54), an orphan GPR54 related to galanin receptors. Endogenous forms composed of 54, 14, and 13 amino acids have been identified. Kisspeptin and GPR54
Jin Li et al.
EMBO reports, 17(2), 178-187 (2015-12-23)
Pancreatic islets of Langerhans contain several specialized endocrine cell types, which are commonly identified by the expression of single marker genes. However, the established marker genes cannot capture the complete spectrum of cellular heterogeneity in human pancreatic islets, and existing

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