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Key Documents

F8506

Sigma-Aldrich

N-Formyl-Met-Phe

≥97% (HPLC)

Synonym(s):

Neutrophil Dysfunction Test Peptide

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About This Item

Empirical Formula (Hill Notation):
C15H20N2O4S
CAS Number:
Molecular Weight:
324.40
MDL number:
UNSPSC Code:
12352200

Assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

CSCCC(NC=O)C(=O)NC(Cc1ccccc1)C(O)=O

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D Hong et al.
Pharmacology, 28(5), 281-288 (1984-01-01)
We investigated the role of protein synthesis in human polymorphonuclear leukocyte (PMN) chemotaxis and luminol-dependent chemiluminescence (CL). We used cycloheximide and puromycin to inhibit protein synthesis, and determined the extent of synthesis by measurement of 14C-amino acid incorporation. With 2-hour
P W Jeffs et al.
International journal of peptide and protein research, 24(5), 442-446 (1984-11-01)
Physical and structural data on two of a series of related N-formyl methionine peptides are reported. The effects of peptide bond N-methylation on chemotactic response and on conformational properties observed in solution, in the solid state and by conformational energy
T C Hunt et al.
Veterinary immunology and immunopathology, 12(1-4), 75-82 (1986-06-01)
The bipolar shape formation assay, previously used to determine the chemotactic potential of various factors for mammalian leucocytes, was tested in the present study with granulocytes of the lesser spotted dogfish, Scyliorhinus canicula. Bipolar shape formation was found to be
Heterochiral N-formyl methionyl peptides. Molecular conformation and crystal structures of N-f-L-Met-D-Phe and N-f-L-Met-D-Phe-OtBu.
D S Eggleston
International journal of peptide and protein research, 31(2), 164-172 (1988-02-01)
R Louis et al.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 24(1), 60-65 (1994-01-01)
We investigated the effects of intravenous injection of methylprednisolone (MPR) compared with placebo (saline) on ex vivo leucocytic histamine release in eight healthy volunteers. All subjects received in a randomized and a single-blind manner the placebo and MPR, 20 mg

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