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EHU061041

Sigma-Aldrich

MISSION® esiRNA

targeting human SNAP23

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TGCACCATTCAGGAACACTTTATATAAATGAGTGGCTTTTTATTTCATATTATTAGTAGTATCATGGTTCCATTACAGGCCTATTAACATCATACATTGTCATTAGTCTTTGAAGAAAAAATATGTAAATATATATGTGTAACATGAGAATTTCTCTCTAAAGCAGGGCTTAAAATTTTTTGGAAAAGTTTGACAAAGCATACCACATGAATTCAGATTTACCTCAATGCTAAGAATTATGTTTAGTTAGGAAAAAGGAAAGTCATTTTGACCTCAGGTAGAAAAATAGATTGCTTTGAGTTTTATGTAGCTTTAGACTTTAAAAAGTTAGAATTTATTCTGTAACTAAAAATTATTTGAAAAAATTATGCCTCTGGTTTAATTATTGGTGATTACACACTCTTTCTCTTACCCTTGTG

Ensembl | human accession no.

ENSG00000092531

NCBI accession no.

NM_003825

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... SNAP23(8773) , SNAP23(8773)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Roxana Khazen et al.
Nature communications, 7, 10823-10823 (2016-03-05)
Human melanoma cells express various tumour antigens that are recognized by CD8(+) cytotoxic T lymphocytes (CTLs) and elicit tumour-specific responses in vivo. However, natural and therapeutically enhanced CTL responses in melanoma patients are of limited efficacy. The mechanisms underlying CTL
Daiki Kinoshita et al.
Molecular biology of the cell, 30(9), 1085-1097 (2019-02-28)
Syntaxin 11 (stx11) is a soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) that is selectively expressed in immune cells; however, its precise role in macrophages is unclear. We showed that stx11 knockdown reduces the phagocytosis of Escherichia coli in interferon-γ-activated

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