Hepa 1-6

92110305, mouse liver, Not specified

• Synonym(s): Hepa 1-6 Cells
• UNSPSC Code: 41106514

Properties

• Product Name: Hepa 1-6, 92110305
• biological source: mouse liver
• growth mode: Adherent
• karyotype: Not specified
• morphology: Not specified
• products: Albumin, alpha-foetoprotein, alpha 1-antitrypsin, amylase
• receptors: Not specified
• technique(s): cell culture | mammalian: suitable
• relevant disease(s): cancer
• shipped in: dry ice
• storage temp.: −196°C

Description

Cell Line Origin

Mouse hepatoma

Cell Line Description

Derived from BW7756 tumour in a C57L mouse. Secretes several liver products including albumin, α-fetoprotein, α 1-antitrypin and amylase.

Application

Hepa 1-6 has been used to study the biodistribution of polymer hydrogel capsules for the delivery of therapeutics.[1] It has also been used to evaluate the potential of interferon regulatory factor-1 (IRF-1) for cytokine gene therapy of hepatocellular carcinoma (HCC).[2]

Culture Medium

DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS).

Subculture Routine

Split sub-confluent cultures (70-80%) 1:2 to 1:4 i.e. seeding at 2-5x10,000 cells/cm² using 0.25% trypsin or trypsin/EDTA; 5% CO₂; 37°C.

Other Notes

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