AV32195

Anti-DBP (AB2) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-D site of albumin promoter (albumin D-box) binding protein
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 34 kDa
• species reactivity: human
• concentration: 0.5 mg - 1 mg/mL
• technique(s): immunohistochemistry: suitable; western blot: suitable
• NCBI accession no.: NP_001343
• UniProt accession no.: Q10586
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... DBP(1628)

Description

General description

Albumin promoter (albumin D-box) D-site binding protein (DBP), a PAR basic region leucine zipper (bZIP) protein, is a transcription factor involved in the diurnal regulation of gene transcription in the brain, liver and kidney. It regulates the expression of proteins such as cholesterol 7 α-hydroxylase P450 gene (CYP7) and kisspeptins (Kiss1).

DBP is known to control the growth of liver cells.

Rabbit polyclonal anti-DBP reacts with bovine, canine, human, mouse, and rat D-site of albumin promoter (albumin D-box) binding proteins.

Immunogen

Synthetic peptide directed towards the N terminal region of human DBP

Application

Rabbit Anti-DBP can be used for western blot applications at a concentration of 0.5-5.0μg/ml. It can also be used for immunohistochemistry at 4-8μg/ml, using paraffin-embedded tissues.

Rabbit polyclonal anti-DBP is used to tag D site of albumin promoter (albumin D-box) binding protein for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of D site of albumin promoter (albumin D-box) binding protein in diurnal regulation of gene expression.

Biochem/physiol Actions

D-site-binding protein (DBP) is a member of the PAR bZIP (proline and acidic amino acid-rich basic leucine zipper) transcription factor family.

Sequence

Synthetic peptide located within the following region: PKEPASCLLKEKERKAALPAATTPGPGLETAGPADAPAGAVVGGGSPRGR

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable