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Sigma-Aldrich

Hydroxyethyl-cellulose

viscosity 90-160 cP, 5 % in H2O(25 °C)

Synonym(s):

Cellosize® EP-09

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About This Item

CAS Number:
9004-62-0
MDL number:
MFCD00072770
UNSPSC Code:
12352201
NACRES:
NA.25

form

powder

color

beige

viscosity

90-160 cP, 5 % in H2O(25 °C)

storage temp.

room temp

InChI

1S/C29H52O21/c1-10-15(34)16(35)24(13(8-33)45-10)49-28-20(39)18(37)25(50-29-26(43-5-4-30)21(40)23(42-3)12(7-32)47-29)14(48-28)9-44-27-19(38)17(36)22(41-2)11(6-31)46-27/h10-40H,4-9H2,1-3H3

InChI key

CWSZBVAUYPTXTG-UHFFFAOYSA-N

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General description

Hydroxyethyl cellulose is a gelling and thickening agent derived from cellulose and is widely used in cosmetics, cleaning solutions and other household products. It is used with hydrophobic drugs in capsule formulations, to improve the drugs dissolution in the gastrointestinal fluids. This process is known as hydrophilization.

Application

Hydroxyethylcellulose is used as a gelling and thickening agent in the development of biostructures for the delivery of hydrophobic drugs. Hydroxyethylcellulose is used in the development of polymer networks and block copolymers useful in separation technology such as capillary electrophoresis and in biofilms and coatings. It is also used for encapsulation of cells in chitosan/glycerophosphate/hydroxyethyl cellulose (chitosan-GP/HEC) gels.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Network-forming polymer in capillary electrophoresis of DNA restriction fragments

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Peter Roughley et al.
Biomaterials, 27(3), 388-396 (2005-08-30)
The suitability of chitosan-based hydrogels as scaffolds for the encapsulation of intervertebral disc (IVD) cells and the accumulation of a functional extracellular matrix mimicking that of the nucleus pulposus (NP) was investigated. The specific hypothesis under study was that the
M H Kleemiss et al.
Electrophoresis, 14(5-6), 515-522 (1993-05-01)
Separation of DNA restriction fragments in dilute buffer solutions of network forming polymers such as linear polyacrylamide (PAA), hydroxyethyl cellulose (HEC) and polyvinylalcohol (PVA) in phosphate buffer were investigated. PVA in buffers already became inhomogeneous after a few separations with
Temperature-responsive self-assembly of charged and unchargedhydroxyethylcellulose-graft-poly(N-isopropylacrylamide) copolymer in aqueous solution.
Phan HT, Zhu K, Kj?niksen AL, Nystrom B.
Coll. Polymer Sci., 289, 993-1003 (2011)
Runmiao Yang et al.
Electrophoresis, 29(7), 1460-1466 (2008-04-04)
We present cationized hydroxyethylcellulose (cat-HEC) synthesized in our laboratory as a novel physically adsorbed coating for CE. This capillary coating is simple and easy to obtain as it only requires flushing the capillary with polymer aqueous solution. A comparative study
A Semalty et al.
Indian journal of pharmaceutical sciences, 72(5), 571-575 (2011-06-23)
Enalapril maleate is used in the treatment of hypertension and angina pectoris. It shows low bioavailability due to high hepatic first pass metabolism. Hence the present work was undertaken to formulate mucoadhesive buccal films of enalapril maleate with an objective
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