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ERMDA471IFCC

Human serum (cystatin C)

ERM®, certified reference material

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About This Item

UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Agency

ERM®

manufacturer/tradename

JRC

application(s)

clinical testing

format

matrix material

storage temp.

−70°C

Related Categories

General description

Certified for cystatin C in human serum.

ERM-DA471IFCC_cert
ERM-DA471IFCC_report
ERM-DA471IFCC_origin

Application


  • Serum biomarker for sarcopenia: A study utilized the serum creatinine/cystatin C ratio as a biomarker for sarcopenia components among different age groups in older ndividuals, underscoring the role of human serum cystatin C in monitoring muscle health and potentially guiding interventions (Fang et al., 2024).

  • Screening of sarcopenia: The investigation demonstrated the efficacy of using serum creatinine-cystatin C based screenings for sarcopenia in community-dwelling older adults, highlighting cystatin C′s significance as a reliable indicator of muscle degradation, which is crucial for early intervention (Matsuzawa et al., 2024).

  • Predictive tool in chronic kidney disease: Research emphasized native T1-mapping combined with human serum cystatin C levels as predictors of renal function decline in chronic kidney disease patients, illustrating cystatin Cs utility in enhancing the diagnosis and management of kidney disease (Shi et al., 2024).

Analysis Note

For more information please see:
ERMDA471/IFCC

Legal Information

ERM is a registered trademark of European Commission

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H312,H412

Hazard Classifications

Acute Tox. 4 Dermal - Aquatic Chronic 3

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Determination of Cystatin C in human serum by isotope dilution mass spectrometry using mass overlapping peptides.
Gonzalez-Antu?a A, et al.
Journal of Proteomics, 112, 141-155 (2015)
Adriano Boasso et al.
Clinical immunology (Orlando, Fla.), 129(1), 132-144 (2008-07-25)
The programmed death (PD)-1 interacts with its ligand (PDL-1) delivering a negative signal to T cells. During human immunodeficiency virus (HIV)-1 infection PD-1 and PDL-1 expressions are increased. Here we show that monocytes and CCR5(+) T cells of HIV-uninfected donors
Bin Ma et al.
Scientific reports, 1, 140-140 (2012-02-23)
Transport of mRNAs to diverse neuronal locations via RNA granules serves an important function in regulating protein synthesis within restricted sub-cellular domains. We recently detected the Huntington's disease protein huntingtin (Htt) in dendritic RNA granules; however, the functional significance of
Lynell W Klassen et al.
Biochemical pharmacology, 76(3), 426-436 (2008-07-05)
Alcohol abuse results in liver injury, but investigations into the mechanism(s) for this injury have been hampered by the lack of appropriate in vitro culture models in which to conduct in depth and specific studies. In order to overcome these
Xiao-Li Huang et al.
Clinical and vaccine immunology : CVI, 16(10), 1504-1516 (2009-08-21)
Human immunodeficiency virus type 1 (HIV-1)-specific T-cell reactivity has been related to protection from disease progression. Optimal T-cell reactivity to HIV-1 presumably requires antigen processing and presentation by professional antigen-presenting cells, particularly dendritic cells (DC). Here we examined whether multiple
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