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EPN

100 μg/mL in acetonitrile, PESTANAL®, analytical standard

Synonym(s):

O-Ethyl O-(4-nitrophenyl) phenylphosphonothioate solution

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About This Item

CAS Number:
Beilstein:
2542580
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

concentration

100 μg/mL in acetonitrile

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture

format

single component solution

storage temp.

2-8°C

SMILES string

CCOP(=S)(Oc1ccc(cc1)[N+]([O-])=O)c2ccccc2

InChI

1S/C14H14NO4PS/c1-2-18-20(21,14-6-4-3-5-7-14)19-13-10-8-12(9-11-13)15(16)17/h3-11H,2H2,1H3

InChI key

AIGRXSNSLVJMEA-UHFFFAOYSA-N

General description

EPN belongs to the class of organophosphorus insecticides extensively used in agriculture for the control of a wide range of insect pests. Its mode of action involves the inhibition of acetylcholinesterase activity in insects.

Application

EPN may be used as an analytical reference standard for the quantification of the analyte in tea and environmental samples using various chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F

Flash Point(C)

2 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Development of enzyme-linked immunosorbent assays for the organophosphorus insecticide EPN
Shim YJ, et al.
Journal of Agricultural and Food Chemistry, 56(24), 11551-11559 (2008)
Simultaneous multi-determination and transfer of eight pesticide residues from green tea leaves to infusion using gas chromatography
Cho K-S, et al.
Food Chemistry, 165, 532-539 (2014)
Analysis of organophosphorus insecticides from environmental samples using solid-phase microextraction
Magdic S, et al.
Journal of Chromatography A, 736(1-2), 219-228 (1996)
S Sugiyama et al.
Japanese journal of pharmacology, 37(1), 39-44 (1985-01-01)
Inhibition of rat liver microsomal carboxylesterase (CEase) by O-ethyl O-p-nitrophenyl phenylphosphonothioate (EPN) and binding of EPN oxygen analog to microsomal CEase were enhanced by addition of NAD or NADP. This was more prominent in addition of NAD than NADP. No
Jee Youn Shim et al.
Journal of agricultural and food chemistry, 58(9), 5241-5247 (2010-04-15)
This study aimed at developing competitive direct and indirect enzyme-linked immunosorbent assays (ELISAs) for the organophosphorus insecticide O-ethyl O-4-nitrophenyl phenylphosphonothioate (EPN) using a monoclonal antibody (mAb). Of the five EPN derivatives (haptens) prepared for use as an immunogen or as

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