MAB8188

Anti-EBV EA-R-p17 Antibody, clone 5B11

clone 5B11, Chemicon^®, from mouse

• Synonym(s): Early Antigen Protein R, Nuclear Antigen, BHRF1
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 300
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 5B11, monoclonal
• species reactivity: human
• manufacturer/tradename: Chemicon^®
• technique(s): ELISA: suitable; immunofluorescence: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• isotype: IgG2a
• shipped in: wet ice

Description

General description

The Early Restricted protein (Ea-R) of Epstein-Bar Virus is encoded by the viral BHFR1 gene. Ea-R is a 17 kDa protein (p17) with protein kinase activity. Ea-R-p17 is a functional homologue of the anti-apoptotic oncoprotein bcl-2, which is expressed during the switch from latency to lytic replication and may be involved in proliferation of EBV infected cells. However, Ea-R-p17 does not appear to be essential for virus replication or transformation of B cells in vitro.

Specificity

Recognizes the 17 kDa Early Restricted Protein (Ea-R-p17) of Epstein-Barr Virus by immunoblot, immunoprecipitation and immunofluorescence.

Application

Anti-EBV EA-R-p17 Antibody, clone 5B11 is an antibody against EBV EA-R-p17 for use in ELISA, IF, IP & WB.

Immunoblotting

Immunoprecipitation

Immunofluorescence

Optimal dilutions must be determined by the end user.

Research Category
Infectious Diseases

Research Sub Category
Infectious Diseases - Viral

Physical form

Format: Purified

Purified immunoglobulin presented as a liquid in 0.02M PBS, 0.25M NaCl, with 0.1% sodium azide.

Storage and Stability

Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable