Claudin-7 is a member of a family of claudins that are tight junction integral membrane proteins with four transmembrane domains and two extracellular loops. Claudin-7 has been shown to be under-expressed in invasive ductal carcinomas and colorectal carcinomas as compared to normal epithelial cells. Claudin-7 differs from other claudins because it has both structural and regulatory functions, regulating the expression of prostate specific antigen.
Immunogen
KLH-conjugated linear peptide corresponding to human Claudin-7.
Application
Anti-Claudin-7 Antibody is an antibody against Claudin-7 for use in WB.
Research Category Cell Structure
Research Sub Category ECM Proteins
Quality
Evaluated by Western Blot in BALB3T3/A31 cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected Claudin-7 in 10 µg of BALB3T3/A31 cell lysate.
Target description
~22 kDa observed
Physical form
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control BALB3T3/A31 cell lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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