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Key Documents

ABF288

Sigma-Aldrich

Anti-NOD4 Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

Protein NLRC5, Caterpiller protein 16.1, CLR16.1, Nucleotide-binding oligomerization domain protein 27, Nucleotide-binding oligomerization domain protein 4

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, human

technique(s)

immunocytochemistry: suitable
immunofluorescence: suitable
western blot: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... NLRC5(84166)

General description

Protein NLRC5, also known as Caterpiller protein 16.1 (CLR16.1) or Nucleotide-binding oligomerization domain protein 27 or Nucleotide-binding oligomerization domain protein 4, and encoded by the gene name NLRC5 or NOD4 or NOD27, may play an important role in regulating the type II interferon signaling pathway. NOD4 is expressed in spleen, thymus, lung, brain, tonsil, heart and prostate. NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.

Immunogen

KLH-conjugated synthetic peptide corresponding to the N-terminus of human NOD4.

Application

Anti-NOD4 Antibody is an antibody against NOD4 for use in western blotting, ICC & immunofluorescence.
Immunocytochemistry Analysis: 10 μg/mL from a representative lot detected NOD4 in HeLa cells.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected NOD4 in HeLa cells.



Quality

Evaluated by Western Blotting in EL4 cell lysate.

Western Blotting Analysis: 1 μg/mL of this antibody detected NOD4 in EL4 cell lysate.

Target description

~205 kDa observed. Uncharacterized bands may be observed in some lysate(s). Uniprot describes 6 isoforms produced by alternative splicing ranging between ~79 kDa and ~206 kDa

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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