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8.55031

Sigma-Aldrich

Rink Amide NovaGel

Novabiochem®

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About This Item

UNSPSC Code:
12352111
NACRES:
NA.22

Quality Level

200

product line

NovaGel
Novabiochem®

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

amine

storage temp.

2-8°C

General description

This resin is prepared by derivatization of aminomethyl NovaGel with the modified Rink linker. NovaGel resins combine many of the excellent properties of PEG-PS-based resins with the high loading efficiency of conventional polystyrene-based supports. In a comparison with Rink amide resin, this resin was found to give superior results in the synthesis of peptides up to 17 amino acids in length [1]. The use of this support in the preparation of oligonucleotide-peptide conjugates has been described [2].

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Linkage

Replaces: 01-64-0286

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.50 - 0.70 mmol/g
Swelling Volume (in DMF): lot specific result
The PEG-PS resin is prepared from aminomethyl copoly(styrene-1 % DVB), 100 - 200 mesh

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

Fmoc SPPS Linkers

Novabiochem® offers a wide range of linkers and derivatized resins for Fmoc solid-phase peptide synthesis with specialized protocols.

Protocols

Peptide Resin Loading Protocols

Review various resins like Merrifield, trityl-based, and hydroxymethyl-functionalized for peptide immobilization for diverse applications.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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