1.04852

Potassium hydrogen carbonate

EMPROVE^® ESSENTIAL, Ph. Eur., BP, USP, FCC, E 501

• Synonym(s): Potassium hydrogen carbonate, Potassium bicarbonate
• Empirical Formula (Hill Notation): CHKO₃
• CAS Number: 298-14-6
• Molecular Weight: 100.12
• MDL number: MFCD00011402
• UNSPSC Code: 12352302
• E Number: E501
• EC Index Number: 206-059-0

Properties

• Agency: BP; Ph. Eur.; USP
• Quality Level: 500
• reg. compliance: FCC
• product line: EMPROVE^® ESSENTIAL
• form: solid
• pH: 8.4-8.6 (20 °C, 99 g/L in H₂O)
• solubility: 362 g/L
• density: 2.17 g/cm³ at 20 °C
• application(s): liquid formulation; pharmaceutical; solid formulation
• storage temp.: 15-25°C
• InChI: 1S/CH2O3.K/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1
• InChI key: TYJJADVDDVDEDZ-UHFFFAOYSA-M

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Potassium hydrogen carbonate (synonym potassium bicarbonate) is a commonly used ingredient in both food and pharmaceutics. In pharmaceutical applications, potassium hydrogen carbonate is primarily used as a source of carbon dioxide in oral formulations such as effervescent tablets or granules.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable