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878100C

Avanti

C17-02:0 PC

Avanti Research - A Croda Brand 878100C

Synonym(s):

1-O-Heptadecyl-2-Acetoyl-sn-Glycero-3-Phosphocholine (C17 PAF)

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About This Item

Empirical Formula (Hill Notation):
C27H56NO7P
CAS Number:
Molecular Weight:
537.71
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 1 mL (878100C-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 878100C

concentration

5 mg/mL (878100C-5mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(C)=O)COCCCCCCCCCCCCCCCCC)=O

General description

C17-02:0 PC, also known as 1-O-heptadecyl-2-acetyl-sn-glycero-3-phosphocholine (C17 PAF) is a platelet activating factor containing ether-linked heptadecyl chain at the sn-1 position and an acetyl group at the sn-2 position.

Biochem/physiol Actions

Platelet-activating factor (PAF) acts as a lipid mediator and is involved in various inflammatory diseases.

Packaging

5 mL Clear Glass Sealed Ampule (878100C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

WGK

WGK 3


Certificates of Analysis (COA)

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Akira Sato et al.
European journal of pharmacology, 745, 46-51 (2014-12-03)
Platelet-activating factor (PAF) is a potent lipid mediator that is implicated in numerous inflammatory diseases. C-reactive protein (CRP) is an acute-phase plasma protein that increases rapidly and dramatically in response to inflammation. In this study, we investigated the effect of
Sunil A Nankar et al.
Biochimie, 95(6), 1196-1207 (2013-02-05)
Apolipoprotein-derived peptides are promising candidates for the treatment of various inflammatory conditions and the main mechanism proposed for the protective action of these peptides includes binding to pro-inflammatory lipid mediators with high affinity and facilitating their sequestration/metabolism/clearance in the body.

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