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Avanti

Differential Ion Mobility System Suitability LIPIDOMIX™ Kit

Synonym(s):

Differential Ion Mobility System Suitability LIPIDOMIX™ Kit

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About This Item

UNSPSC Code:
12352211
NACRES:
NA.25

biological source

bovine heart

form

chloroform:methanol solution

manufacturer/tradename

Avanti Research™ - A Croda Brand

application(s)

lipidomics
metabolomics

shipped in

dry ice

storage temp.

−20°C

General description

The Differential Ion Mobility System Suitability LIPIDOMIX™ system provides pre-mixed synthetic lipid standards combined with a natural lipid extract to provide a system suitability standard that allows you to confirm visualization and separation of each lipid class. This standard and protocol was developed in collaboration with Paul Baker and Leo Wang of SCIEX. The standard is designed to ensure proper instrument set-up and allow for easy method development using ion mobility platforms. The combination of synthetic lipids with the natural lipid extract form a lipid population representative of a typical sample.

Application

Differential Ion Mobility System Suitability LIPIDOMIX™ Kit has been used as a lipid standard in chromatography methods.

Components

The Differential Ion Mobility System Suitability LIPIDOMIX Kit contains two vials.

Bovine Heart Extract is supplied in one vial as 25 mg in 1 mL of chloroform.

The second vial is supplied in 0.5 mL of chloroform:methanol (1:1) and contains the following components each at 1 mg/mL unless otherwise noted.

  • Cholesterol
  • 18:1 TG
  • 18:1 SM
  • 18:1 Ceramide
  • 18:1 Lyso PC
  • 19:0 Chol Ester
  • 14:1 DG
  • 14:1 CA
  • 14:1 PC
  • 14:1 PS
  • 14:1 PG
  • 14:1 PE
  • 14:1 PI (0.25 mg/mL)
  • 14:1 PA

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC

Kit Components Also Available Separately

Product No.
Description
SDS
  • 171201CHeart Extract Total, Avanti Research™ - A Croda BrandSDS

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 1 - STOT SE 3

Target Organs

Eyes,Central nervous system, Liver,Kidney, Respiratory system

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Unbiased Lipidomics and Metabolomics of Human Brain Samples
Biomarkers for Alzheimer?s Disease Drug Development, 255-269 (2018)
Comprehensive lipidomic analysis of human plasma using multidimensional liquid-and gas-phase separations: Two-dimensional liquid chromatography-mass spectrometry vs. liquid chromatography-trapped-ion-mobility-mass spectrometry
Baglai A, et al.
Journal of Chromatography A, 1530, 90-103 (2017)
Catherine G Vasilopoulou et al.
Nature communications, 11(1), 331-331 (2020-01-18)
A comprehensive characterization of the lipidome from limited starting material remains very challenging. Here we report a high-sensitivity lipidomics workflow based on nanoflow liquid chromatography and trapped ion mobility spectrometry (TIMS). Taking advantage of parallel accumulation-serial fragmentation (PASEF), we fragment

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