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Key Documents

CF0018

Sigma-Aldrich

Pyrazolyltetrafluorobromoethane

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About This Item

Linear Formula:
C5H3BrF4N2
CAS Number:
MDL number:
UNSPSC Code:
12352101

form

liquid

reaction suitability

reaction type: C-C Bond Formation

Application

Pyrazolyltetrafluorobromoethane is a fluoroalkylbromide that is a radical source of the pyrazolyl tetrafluoroethyl moiety. Alternatively, it can be also selectively metallated at the fluorinated carbon with Turbo Grignard reagent at low temperatures and the resulting thermally unstable anion can act as a nucleophilic fluoroalkylation reagent towards a wide variety of electrophiles, such as aldehydes, ketones or sulfonylimines.

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Legal Information

Product of CF Plus Chemicals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Articles

Fluoroalkylation toolbox expands with various reagents for late-stage fluoroalkylation in organic synthesis and medicinal chemistry.

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