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CF0016

Sigma-Aldrich

4-Ethoxycarbonylphenoxytetrafluorobromoethane

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About This Item

Linear Formula:
C11H9BrF4O3
CAS Number:
MDL number:
UNSPSC Code:
12352101

form

liquid

reaction suitability

reaction type: C-C Bond Formation

Application

4-Ethoxycarbonylphenoxytetrafluorobromoethane is a fluoroalkylbromide that is a radical source of the 4-ethoxycarbonylphenoxytetrafluoroethyl moiety. Alternatively, it can also be selectively metallated at the fluorinated carbon with Turbo Grignard reagent at low temperatures resulting in a thermally unstable anion that can act as a nucleophilic fluoroalkylation reagent towards a wide variety of electrophiles, such as aldehydes, ketones or sulfonylimines. The ester group can be transformed to other derivatives, building molecular complexity.

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Legal Information

Product of CF Plus Chemicals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Fluoroalkylation toolbox expands with various reagents for late-stage fluoroalkylation in organic synthesis and medicinal chemistry.

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