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About This Item
Linear Formula:
HOC6H4CH=C(CN)CO2H
CAS Number:
Molecular Weight:
189.17
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
Assay
98%
mp
232 °C (dec.) (lit.)
SMILES string
OC(=O)\C(=C\c1cccc(O)c1)C#N
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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H K Metcalfe et al.
Clinical science (London, England : 1979), 71(6), 755-761 (1986-12-01)
The rate of efflux of ketone bodies has been studied in isolated hepatocytes prepared from starved rats and preloaded with D-3-[14C]hydroxybutyrate. Efflux of ketone bodies was temperature-dependent, saturable and inhibited by alpha-cyano-3-hydroxycinnamate and phloretin. The rate of efflux was also
S M Hutson et al.
The Journal of biological chemistry, 260(26), 14189-14193 (1985-11-15)
Efflux of branched chain alpha-keto acids from preloaded rat heart mitochondria was slow at low external pH. Efflux was first order, and measured rate constants, kappa efflux, were 0.104 +/- 0.005 and 0.115 +/- 0.006 min-1 for alpha-ketoisovalerate and alpha-ketoisocaproate
Rie Hosoi et al.
Brain research, 1253, 69-73 (2008-12-17)
To investigate the regulation mechanism of (14)C-acetate uptake in astrocytes, uptake experiments with cultured rat astrocytes were performed. In this study, we used a relatively low concentration (0.0185 mM) of (14)C-acetate. The uptake was dependent on pH and acetate concentration
J P Monson et al.
Clinical science (London, England : 1979), 62(4), 411-420 (1982-04-01)
1. The rate of uptake in 15 s of L- and D-lactate was studied in isolated hepatocyte preparations from starved rats. 2. Observations were also made of the effect of different concentrations of unlabelled L- and D-lactate on L-[14C]- and
I E O'Neill et al.
Comparative biochemistry and physiology. B, Comparative biochemistry, 83(3), 595-598 (1986-01-01)
Isolated kidney tubules synthesize glucose actively from fructose, lactate, glycerol and pyruvate and, to a lesser extent, from a variety of amino acids. Ethanol stimulated gluconeogenesis from pyruvate and inhibited it from lactate. The aminotransferase inhibitor, aminooxyacetate, greatly reduced synthesis
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