TREM2
triggering receptor expressed on myeloid cells 2
Synonyms:
TREM-2, Trem2a, Trem2b, Trem2c
Species:
Human TREM2 (54209), Mouse Trem2 (83433), Rat Trem2 (301227), sheep TREM2 (101105447), cow TREM2 (506467), domestic cat TREM2 (101099297), dog TREM2 (608965), chicken TREM2 (419920), naked mole-rat Trem2 (101717064), domestic guinea pig Trem2 (100720722)
UniProtKB ID:
Gene ID:
- Human(54209) Summary: This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
- Mouse(83433) triggering receptor expressed on myeloid cells 2
- Rat(301227) triggering receptor expressed on myeloid cells 2
- sheep(101105447) triggering receptor expressed on myeloid cells 2
- cow(506467) triggering receptor expressed on myeloid cells 2
- domestic cat(101099297) triggering receptor expressed on myeloid cells 2
- dog(608965) triggering receptor expressed on myeloid cells 2
- chicken(419920) triggering receptor expressed on myeloid cells 2
- naked mole-rat(101717064) triggering receptor expressed on myeloid cells 2
- domestic guinea pig(100720722) triggering receptor expressed on myeloid cells 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-TREM-2 Antibody, clone 1I11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse
Application
affinity binding assay
flow cytometry
immunocytochemistry
western blot
flow cytometry
immunocytochemistry
western blot
Anti-TREM-2 Antibody, clone 10H4.2, clone 10H4.2, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-TREM-2, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-TREM-2 Antibody, clone 78, clone 78, from rat,
Species Reactivity
human, mouse, rat
Application
flow cytometry
immunocytochemistry
immunoprecipitation (IP)
inhibition assay
western blot
immunocytochemistry
immunoprecipitation (IP)
inhibition assay
western blot