IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
Synonyms:
IMPD2, IMPDH-II
Species:
Human IMPDH2 (3615), Mouse Impdh2 (23918), Rat Impdh2 (301005), dog IMPDH2 (476630), Zebrafish impdh2 (317745), domestic guinea pig Impdh2 (100730768), naked mole-rat Impdh2 (101701391), domestic cat IMPDH2 (101080693), cow IMPDH2 (511969), sheep IMPDH2 (101107823) ...More
UniProtKB ID:
Gene ID:
- Human(3615) Summary: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]
- Mouse(23918) inosine 5'-phosphate dehydrogenase 2
- Rat(301005) IMP (inosine 5'-monophosphate) dehydrogenase 2
- dog(476630) IMP (inosine 5'-monophosphate) dehydrogenase 2
- Zebrafish(317745) IMP (inosine monophosphate) dehydrogenase 2
- domestic guinea pig(100730768) IMP (inosine 5'-monophosphate) dehydrogenase 2
- naked mole-rat(101701391) IMP (inosine 5'-monophosphate) dehydrogenase 2
- domestic cat(101080693) IMP (inosine 5'-monophosphate) dehydrogenase 2
- cow(511969) IMP (inosine 5'-monophosphate) dehydrogenase 2
- sheep(101107823) IMP (inosine 5'-monophosphate) dehydrogenase 2
- Domestic Rabbit(100355621) IMP (inosine 5'-monophosphate) dehydrogenase 2
- chicken(416058) IMP (inosine 5'-monophosphate) dehydrogenase 2
- Horse(100063255) IMP (inosine 5'-monophosphate) dehydrogenase 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti IMPDH2 Antibody, clone 23GB6670, Rabbit Monoclonal, clone 23GB6670, recombinant rabbit monoclonal, expressed in HEK293 cells,
Species Reactivity
human, rat
Application
flow cytometry
western blot
western blot
Anti-IMPDH2 Mouse mAb (1E12-B6), liquid, clone 1E12-B6, Calbiochem®,
Species Reactivity
human
Application
Small Molecule - Inhibitor
Product Number
Description
Species
Mycophenolate Mofetil, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Proteins
Product Number
Description
Species
Inosine Monophosphate Dehydrogenase Type II human, recombinant, expressed in E. coli,
Species
human