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Merck

HTR7

5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled

Synonyms:
5-HT7
Species:
UniProtKB ID:
Gene ID:
  • Human(3363) Summary: The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends. [provided by RefSeq, Jul 2008]
  • Mouse(15566) 5-hydroxytryptamine (serotonin) receptor 7
  • Rat(65032) 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
  • Domestic Rabbit(100009356) 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
  • sheep(101122994) 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
  • dog(477762) 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
  • Horse(100009688) 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
  • naked mole-rat(101719078) 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
  • domestic cat(101092146) 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
  • cow(538510) 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
  • chicken(423794) 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
  • domestic guinea pig(100135549) 5-hydroxytryptamine (serotonin) receptor 7

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Small Molecule - Agonist

Product Number
Description
Species
Quipazine maleate salt, ,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
DCEBIO, ≥98% (HPLC), solid,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
SB-269970 hydrochloride, powder, ≥98% (HPLC),
Species
human
5-Methoxytryptamine, 97%,
Species
rat, human
1-(2-Methoxyphenyl)piperazine, 98%,
Species
mouse, rat
Metergoline, ,
Species
human, rat
Amisulpride for system suitability, British Pharmacopoeia (BP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-5HT7 Receptor Antibody, clone 4E6D2, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Mifepristone, ≥98%,
Species
human, mouse, rat
Harmaline, ≥95%,
Species
human, rat

Small Molecule - Ligand

Product Number
Description
Species
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Species
human

Small Molecule - Metabolite

Product Number
Description
Species
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Species
human

Small Molecule - Precursor

Product Number
Description
Species
5-Hydroxy-L-tryptophan, powder,
Species
human

Proteins

Product Number
Description
Species
5-HT7 Serotonin Receptor from rat, recombinant, expressed in HEK 293 cells,
Species
rat
ChemiSCREEN Membrane Preparation Recombinant Human 5-HT₇ Serotonin Receptor, Human 5-HT7 GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human HTR7,
Species
human