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Merck

HTR1A

5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

Synonyms:
5-HT-1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, G-21, PFMCD
Species:
UniProtKB ID:
Gene ID:
  • Human(3350) Summary: This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]
  • Mouse(15550) 5-hydroxytryptamine (serotonin) receptor 1A
  • Rat(24473) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • chicken(431581) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • naked mole-rat(101718872) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • dog(487230) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • domestic guinea pig(100301563) 5-hydroxytryptamine (serotonin) receptor 1A
  • cow(407137) 5-hydroxytryptamine (serotonin) receptor 1A
  • Horse(100009683) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • domestic cat(101101542) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • Domestic Rabbit(100008780) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • sheep(101105852) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

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Small Molecule - Agonist

Product Number
Description
Species
Xaliproden hydrochloride, ≥97% (HPLC), solid,
Species
human
Bifeprunox mesylate, ≥98% (HPLC),
Species
human
Pindolol, ≥98% (TLC), powder,
Species
human
Oxymetazoline hydrochloride, ≥99%, solid,
Species
human
Quipazine maleate salt, ,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
DCEBIO, ≥98% (HPLC), solid,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
1-(3-Methoxyphenyl)piperazine, 95%,
Species
rat
WAY-100635 maleate salt, powder,
Species
human
GR 103691, ≥98% (HPLC), solid,
Species
rat
1-(4-Methoxyphenyl)piperazine, 97%,
Species
mouse, rat
Alverine citrate salt, ,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Serotonin Antibody, clone YC5/45, culture supernatant, clone YC5/45, Chemicon®,
Species Reactivity
human, lizard, mouse, pig, rabbit, rat
Application
immunohistochemistry
Anti-Serotonin Receptor 1A Antibody, serum, Chemicon®,
Species Reactivity
rat
Application
immunohistochemistry
Anti-Serotonin receptor 1A Antibody, clone 19A9.2, clone 19A9.2, from mouse,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot

Small Molecule - Blocker

Product Number
Description
Species
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
1,2,3,4-Tetrahydroisoquinoline, 95%,
Species
rat, human
Mifepristone, ≥98%,
Species
human, mouse, rat
Harmaline, ≥95%,
Species
human, rat

Small Molecule - Ligand

Product Number
Description
Species
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Species
human

Small Molecule - Metabolite

Product Number
Description
Species
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Species
human

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
BP897, >98% (HPLC), solid,
Species
human, rat
Mifepristone, ≥98%,
Species
human, mouse, rat

Small Molecule - Precursor

Product Number
Description
Species
5-Hydroxy-L-tryptophan, powder,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human HTR1A,
Species
human