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Merck

GABRB1

gamma-aminobutyric acid (GABA) A receptor, beta 1

Synonyms:
Species:
Human GABRB1 (2560), Mouse Gabrb1 (14400), Rat Gabrb1 (25450), Zebrafish gabrb1 (100331377), sheep GABRB1 (101122358), naked mole-rat Gabrb1 (101717539), domestic guinea pig Gabrb1 (100719515), domestic cat GABRB1 (101097640), dog GABRB1 (100687745), cow GABRB1 (282239)
UniProtKB ID:
P18505, B2R6U7, Q16166, Q8TBK3
Gene ID:
  • Human(2560) Summary: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008]
  • Mouse(14400) gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
  • Rat(25450) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • Zebrafish(100331377) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • sheep(101122358) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • naked mole-rat(101717539) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • domestic guinea pig(100719515) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • domestic cat(101097640) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • dog(100687745) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • cow(282239) gamma-aminobutyric acid (GABA) A receptor, beta 1

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Small Molecule - Agonist

Product Number
Description
Species
G002
Isoguvacine hydrochloride, solid,
Species
human
G019
Muscimol hydrobromide, ≥98% (HPLC), solid,
Species
human
A2129
γ-Aminobutyric acid, ≥99%,
Species
human, rat
B4388
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
P2016
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Species
human
BP1031
Propofol, British Pharmacopoeia (BP) Reference Standard,
Species
human
G7795
Ganaxolone, ≥98% (HPLC), solid,
Species
human, mouse
D126608
2,6-Diisopropylphenol, 97%,
Species
human
A6981
Acamprosate calcium, ≥98% (HPLC), powder,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
P162
Pregnenolone sulfate sodium salt, ,
Species
human
P1675
Picrotoxin, powder,
Species
human
P2016
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Species
human
G7795
Ganaxolone, ≥98% (HPLC), solid,
Species
human, mouse
D126608
2,6-Diisopropylphenol, 97%,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
SAB5702231
Anti-GABA A Receptor beta 1 (GABRB1) Antibody, clone 1Q3A9, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
AB9680
Anti-GABA A Receptor β 1 Antibody, Chemicon®, from rabbit,
Species Reactivity
human, mouse, rat
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
N142
NO-711 hydrochloride, ≥98% (HPLC),
Species
human
D126608
2,6-Diisopropylphenol, 97%,
Species
human
Y0002134
Topiramate, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
B4388
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

esiRNA

Product Number
Description
Species
EHU002071
MISSION® esiRNA, targeting human GABRB1,
Species
human
EMU077451
MISSION® esiRNA, targeting mouse Gabrb1,
Species
mouse