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Merck

FOLR2

folate receptor 2 (fetal)

Synonyms:
BETA-HFR, FBP, FBP/PL-1, FR-BETA, FR-P3
Species:
UniProtKB ID:
Gene ID:
  • Human(2350) Summary: The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14276) folate receptor 2 (fetal)
  • Rat(293154) folate receptor 2 (fetal)
  • sheep(101121452) folate receptor 2 (fetal)
  • dog(476816) folate receptor 2 (fetal)
  • domestic cat(101095853) folate receptor 2 (fetal)
  • cow(507672) folate receptor 2 (fetal)

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-FOLR2 PE produced in mouse, ,
Species Reactivity
human
Application
flow cytometry

Proteins

Product Number
Description
Species
Folate Receptor 2 human, recombinant, expressed in CHO cells, ≥95% (SDS-PAGE),
Species
human