DNMT1
DNA (cytosine-5-)-methyltransferase 1
Synonyms:
ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT
Species:
Human DNMT1 (1786), Mouse Dnmt1 (13433), Rat Dnmt1 (84350), Goat DNMT1 (100861294), Zebrafish dnmt1 (30430), domestic cat DNMT1 (101093502), chicken DNMT1 (396011), dog DNMT1 (476715), sheep DNMT1 (443549), naked mole-rat Dnmt1 (101712352) ...More
UniProtKB ID:
Gene ID:
- Human(1786) Summary: DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
- Mouse(13433) DNA methyltransferase (cytosine-5) 1
- Rat(84350) DNA (cytosine-5-)-methyltransferase 1
- Goat(100861294) DNA (cytosine-5-)-methyltransferase 1
- Zebrafish(30430) DNA (cytosine-5-)-methyltransferase 1
- domestic cat(101093502) DNA (cytosine-5-)-methyltransferase 1
- chicken(396011) DNA (cytosine-5-)-methyltransferase 1
- dog(476715) DNA (cytosine-5-)-methyltransferase 1
- sheep(443549) DNA (cytosine-5-)-methyltransferase 1
- naked mole-rat(101712352) DNA (cytosine-5-)-methyltransferase 1
- cow(281119) DNA (cytosine-5-)-methyltransferase 1
- domestic guinea pig(100717406) DNA (cytosine-5-)-methyltransferase 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Dnmt1 Antibody, clone DNM-2C1, clone DNM-2C1, from rat,
Species Reactivity
human
Application
ChIP
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-DNMT1 Antibody, Ac-4K, from rabbit,
Species Reactivity
human, mouse, rat
Application
dot blot
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-Phospho-Dnmt1(Ser714) Antibody, from rabbit,
Species Reactivity
human
Application
ELISA
dot blot
western blot
dot blot
western blot
Anti-DNMT1 Antibody, clone 1L14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, canine, feline, human, monkey, mouse, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
5-Azacytidine, Hybri-Max™, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma,
Species
human