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Merck

COL18A1

collagen, type XVIII, alpha 1

Synonyms:
KNO, KNO1, KS
Species:
UniProtKB ID:
Gene ID:
  • Human(80781) Summary: This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
  • Mouse(12822) collagen, type XVIII, alpha 1
  • Rat(85251) collagen, type XVIII, alpha 1
  • chicken(373978) collagen, type XVIII, alpha 1
  • domestic cat(101086496) collagen, type XVIII, alpha 1
  • dog(100687767) collagen, type XVIII, alpha 1
  • dog(100126771) collagen, type XVIII, alpha 1
  • sheep(101106232) collagen, type XVIII, alpha 1
  • naked mole-rat(101705854) collagen, type XVIII, alpha 1
  • domestic guinea pig(100733184) collagen, type XVIII, alpha 1
  • Zebrafish(564123) collagen type XVIII, alpha 1
  • cow(508076) collagen, type XVIII, alpha 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-COL18A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-Endostatin Antibody, clone 1837.46, clone 1837.46, Upstate®, from mouse,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Anti-Endostatin Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
Endostatin human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human COL18A1,
Species
human
MISSION® esiRNA, targeting mouse Col18a1,
Species
mouse